The limits are published alongside the reasoning.
- Evidence tiers
Every article carries an explicit evidence tier, so established biology is never presented as if it were clinical proof.
Read the claim ledger - What this does not prove
Mechanistic pieces are required to state their own limits and the competing explanations that would fit the same data.
See the counterarguments - Published corrections
Where the reasoning has been revised, the revision is recorded rather than quietly edited away.
Review the standards
Pick the sentence that sounds like your situation.
- Why does my SIBO keep coming back?
- Are SIBO breath tests actually reliable?
- Why don't antihistamines settle my symptoms?
- Can I have mast cell activation with normal tryptase?
- Why won't my Long COVID symptoms resolve?
- Why did COVID trigger this in me and not others?
- Why are my labs normal when I feel terrible?
- Why doesn't my stool test match my symptoms?
- Why does every protocol stop working after two weeks?
- Why did butyrate or probiotics make me worse?
- What do bile acids have to do with my gut symptoms?
- Can gut health affect my hormones and egg quality?
Educational mechanistic writing. It does not diagnose, and it does not replace the clinician treating you.
Seven mechanistic threads run through this library.
Recurrent SIBO & breath-test interpretation
16 articles · recurrent SIBO
Mast-cell activation, tryptase & histamine
23 articles · mast cell activation
Long COVID, post-viral gut–immune & POTS
18 articles · Long COVID gut symptoms
Colonocyte bioenergetics, butyrate & oxygen
20 articles · colonocyte bioenergetics
Bile acids, TUDCA & C. difficile ecology
7 articles · bile acid dysfunction
Gut–hormone axis, fertility & estrobolome
8 articles · gut microbiome and fertility
Lab-pattern interpretation
6 articles · lab pattern interpretation
3 articles
- MCAS & Mast Cells· October 23, 2026· 28 min· Mechanistic inference
Why Progesterone Calms One Woman but Sends Another Into Panic: The Hidden Biology of Hormonal Sensitivity
Why women can experience severe anxiety, insomnia, panic, and emotional changes despite normal hormone tests—and what allopregnanolone, GABA receptors, childhood trauma, neuroinflammation
#hormone#gut#progesterone - SIBO· October 7, 2026· 20 min· Mechanistic inference
When the Gut Changes, the Brain Does Not Read the Diagnosis: What One Pediatric Autism/ADHD Case Taught Me About Phenols, Mucosal Immunity, FMT, Streptococcus, and Metabolic State
I have been working through a pediatric case that has made me think deeply about the way we approach children with autism, ADHD, childhood apraxia of speech, PANS-like symptoms, gastrointestinal dysfunction, histamine intolerance, unusual
#gut#autism#adhd - healthy-lifestyle· March 27, 2026· 44 min· Mechanistic inference
Why Your Gut Won’t Heal: The Real Reason Chronic Gut Disease Keeps Coming Back
By Mohammed Attallah | Independent Systems Biology Researcher You have been sick for a long time. Not the kind of sick that shows up on a standard blood test. The kind that shows up at 2am when you are bloated, exhausted, and staring at the ceiling, calculating how many days it h
#healthy-lifestyle#health#healthcare
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