Methodology

How I work.

A two-gate intake and one arc: a written mechanistic re-read of the case, translated into a personalized intervention framework for your medical team.

Gate 1

Triage

A brief intake form establishes whether the case is a fit for mechanistic analysis and whether BiomeLogic can offer something the existing clinical team cannot. Most prospective clients begin and end here, with a written response either declining or inviting Gate 2 submission.

Begin the Gate 1 form →
Gate 2

Full case submission

Accepted prospects submit their full case packet: medical records, prior labs, imaging, current medication and supplement regimen, and a structured timeline. Review takes place before the live session.

Case reconstruction

From records to a causal reading.

The same canvas is used for every case: what arrived, how it was reconstructed, and what is written up at the end.

Input

What arrives

  • Prior labs and imaging, in original form
  • Medication, supplement, and antimicrobial history
  • Symptom timeline with onset and inflection points
  • What has already been tried, and what happened

Nothing is discarded for being inconvenient. Contradictory findings are kept on the canvas.

Reconstruction

How it is read

  • Findings mapped onto Host Capacity Model axes
  • Upstream candidates separated from downstream readouts
  • Competing explanations held in parallel, not collapsed
  • Each claim graded by the strength of evidence behind it

The goal is a causal ordering, not a label. Where the ordering is uncertain, that uncertainty is written down.

Output

What is delivered

  • A written mechanistic narrative of the specific case
  • Ranked candidate drivers with the reasoning shown
  • Contradictions and unresolved questions, named
  • Discussion points structured for the licensed care team

Educational analysis for clinician discussion. Implementation stays with your prescribers.

  • Contradictions are preserved

    A finding that does not fit the leading hypothesis is annotated rather than dropped. It is often the most informative part of a case.

  • Evidence is tiered

    Mechanistic, observational, and interventional support are marked separately, so nothing reads stronger than the literature allows.

  • Records stay confidential

    Case material is handled privately and is never used as public example content without explicit written permission.

Standard of evidence

How a mechanistic claim earns its place.

Nothing enters a written synthesis because it sounds plausible. Each mechanism proposed for your case is traced back to primary literature, graded by how directly that literature supports it, and paired with what would falsify it.

  1. Mechanism, not label

    A diagnosis names a pattern. The analysis asks what upstream failure would produce that pattern, and whether one failure explains several of your findings at once.

  2. Traced to primary literature

    Each proposed mechanism is anchored in published research, mapped in the public evidence maps rather than asserted privately.

  3. Graded by strength

    Well-replicated human evidence is distinguished from mechanistic inference and from animal or in-vitro work. Weak support is labelled weak.

  4. Stated so it can be wrong

    Every reading names what would contradict it. A framework that cannot be falsified is not doing analytical work.

What you receive

The Comprehensive Systems-Biology Case Analysis.

$850 USD. Reconstruct the case, identify the leverage points, and build a personalized intervention framework for clinician review. A complete case-analysis engagement, with four weeks of reasonable clarification email follow-up after the written analysis is delivered. A substantial new batch of testing, or a major re-reading of the case, is separate paid re-analysis.

  1. 01

    Full case review

    Records, labs, imaging, prior workups, medication and supplement history are read closely before the session. Patterns are mapped against the Host Capacity Model.

  2. 02

    Live session

    A working call to walk through the mechanistic interpretation, test it against your lived experience, and refine the model with information that doesn't appear in records.

  3. 03

    Written mechanistic summary

    A delivered document: the proposed causal framework for your case, the upstream and downstream mechanisms in play, and a structured set of mechanistic hypotheses to bring to your clinical team.

  4. 04

    Personalized intervention framework

    Personalized intervention framework — including prioritized targets, phased sequencing, supplement/nutrient options and specific product examples when relevant — prepared for review with your medical team.

  5. 05

    Physician review and supervised implementation

    The framework is written to be handed to your physician or medical team, who decide what is appropriate, authorise it, and supervise anything that is acted on.

Working with BiomeLogic from outside the United States

BiomeLogic is not a country-specific service and there is no separate international offering. The same work is delivered the same way wherever you are.

How it runs
Remote (video call) — asynchronous written analysis plus one live session. Nothing depends on you being in the same place, or awake at the same time, as anyone else.
Scheduling the live session
The workable scheduling window has not been published. Rather than imply a coverage claim that has not been confirmed, times are agreed directly with you when the session is booked.
Fees and payment
Fees are charged in USD ($850). Payment route: Stripe, which accepts international cards. Your bank’s conversion and any card fees are outside BiomeLogic’s control.
Jurisdiction and scope
Educational analysis and a personalized intervention framework for your medical team to review—not diagnosis, prescribing, medical supervision, or emergency care. That boundary does not change by country: no clinical care is provided in any jurisdiction, nothing is prescribed anywhere, and no clinician–patient relationship is created.
Who the written output is for
The written synthesis is written to be read by your own licensed clinician, wherever they practise. It is discussion material for that conversation, not an instruction to them or to you.
Boundaries

What this is not.

BiomeLogic does not replace your clinical team. The analysis produced in a consultation is mechanistic and educational: it describes what the evidence suggests may be driving a picture, what would distinguish one explanation from another, and which intervention targets follow from it. BiomeLogic may identify and organize potential intervention options — nutritional, supplemental, behavioral or other mechanistically relevant strategies — for educational and research discussion with your licensed healthcare team. BiomeLogic does not diagnose disease, prescribe, authorise, or medically supervise treatment. Anything acted on — medications, supplements, dose changes, monitoring — is decided, authorised and supervised by your licensed clinicians.

Every consultation is analysed personally, so the work is done one case at a time. If your case has outpaced what your current team can analyse, the door begins at Gate 1.