The limits are published alongside the reasoning.
- Evidence tiers
Every article carries an explicit evidence tier, so established biology is never presented as if it were clinical proof.
Read the claim ledger - What this does not prove
Mechanistic pieces are required to state their own limits and the competing explanations that would fit the same data.
See the counterarguments - Published corrections
Where the reasoning has been revised, the revision is recorded rather than quietly edited away.
Review the standards
Pick the sentence that sounds like your situation.
- Why does my SIBO keep coming back?
- Are SIBO breath tests actually reliable?
- Why don't antihistamines settle my symptoms?
- Can I have mast cell activation with normal tryptase?
- Why won't my Long COVID symptoms resolve?
- Why did COVID trigger this in me and not others?
- Why are my labs normal when I feel terrible?
- Why doesn't my stool test match my symptoms?
- Why does every protocol stop working after two weeks?
- Why did butyrate or probiotics make me worse?
- What do bile acids have to do with my gut symptoms?
- Can gut health affect my hormones and egg quality?
Educational mechanistic writing. It does not diagnose, and it does not replace the clinician treating you.
Seven mechanistic threads run through this library.
Recurrent SIBO & breath-test interpretation
13 articles · recurrent SIBO
Mast-cell activation, tryptase & histamine
17 articles · mast cell activation
Long COVID, post-viral gut–immune & POTS
12 articles · Long COVID gut symptoms
Colonocyte bioenergetics, butyrate & oxygen
18 articles · colonocyte bioenergetics
Bile acids, TUDCA & C. difficile ecology
5 articles · bile acid dysfunction
Gut–hormone axis, fertility & estrobolome
3 articles · gut microbiome and fertility
Lab-pattern interpretation
5 articles · lab pattern interpretation
2 articles
- Case Reasoning· August 18, 2026· 24 min· Clinical pattern observation
Long COVID, Candida, and Klebsiella: When the Gut Loses Its Ecological Control
Post-COVID cases repeatedly show loss of ecological control rather than a single pathogen: Candida and Klebsiella expansion as a readout of failed colonization resistance. What that pattern implies for interpretation rather than eradication.
#long-covid#post-viral#candida - Frameworks· August 17, 2026· 9 min· HCM interpretation
How Bile Acids Suppress C. difficile and Why the Same Chemistry Can Harm the Host
The same bile-acid chemistry that suppresses C. difficile germination can injure the host epithelium at higher exposure. A dose- and context-dependent reading of bile-acid ecology rather than a good/bad framing.
#bile-acids#c-difficile#secondary-bile-acids
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