- Frameworks·May 28, 2026· 19 min·HCM interpretationEducational only
What Actually Causes POTS? A Mechanistic Reading of Postural Orthostatic Tachycardia Syndrome
POTS is not one disease. Four mechanistically distinct pathways — post-viral autonomic ganglion dysfunction, gut-driven vagal dysregulation, connective-tissue-mediated venous pooling, and primary deconditioning — produce the same phenotype. Each needs different intervention. A Host Capacity Model stratification of why standard POTS treatment helps some patients and not others, and how to tell which pathway is dominant in a given case.
#pots#postural-orthostatic-tachycardia-syndrome#dysautonomia#long-covid#heds#mcas#host-capacity-model#autonomic-dysfunction#vagal-nerve#cd38#nadRead mechanism → - Host Capacity Model·May 14, 2026· 28 min·Mechanistic inferenceEducational only
Why hEDS, POTS, and MCAS Almost Always Come Together: The Mechanistic Triad and the Upstream Lesion Standard Medicine Doesn't Treat
Why hEDS, POTS, and MCAS cluster as one integrated illness — three faces of a structural vulnerability decompensating against a shared bioenergetic capacity ceiling.
#heds#pots#mcas#host-capacity#mitochondria#connective-tissue#case-reasoningRead mechanism →
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