2 articles
- Frameworks· May 28, 2026· 19 min· HCM interpretation
What May Be Driving POTS? A Mechanistic Reading of Postural Orthostatic Tachycardia Syndrome
POTS may not be one disease. At least four candidate mechanistic pathways — post-viral autonomic ganglion dysfunction, gut-driven vagal dysregulation, connective-tissue-mediated venous pooling, and primary deconditioning — produce the same phenotype. Each needs different intervention. A Host Capacity Model stratification of why standard POTS treatment helps some patients and not others, and how to tell which pathway is dominant in a given case.
#pots#postural-orthostatic-tachycardia-syndrome#dysautonomia - Host Capacity Model· May 14, 2026· 28 min· Mechanistic inference
Why hEDS, POTS, and MCAS Almost Always Come Together: The Mechanistic Triad and the Upstream Lesion Standard Medicine Doesn't Treat
Why hEDS, POTS, and MCAS cluster as one integrated illness — three faces of a structural vulnerability decompensating against a shared bioenergetic capacity ceiling.
#heds#pots#mcas
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