3 articles
- Frameworks· June 3, 2026· 3 min· HCM interpretation
The Gut Biomarker Almost No One Tests
One of the most consistent patterns I keep finding in complex gut cases is something that rarely gets discussed: low Secretory IgA (sIgA).
#biomarkers#stool-testing#lab-interpretation - Host Capacity Model· May 21, 2026· 23 min· Mechanistic inference
Why Probiotics Make You Sicker, Not Better: The Six Mechanisms Driving Probiotic Failure in MCAS, SIBO, Histamine Intolerance, and Long COVID, and Why The Field Has Been Asking The Wrong Question
What the research actually shows about why patients with chronic gut dysfunction react badly to the most widely recommended supplement in functional medicine, and where the actual lesion lives.
#probiotics#histamine#d-lactate - Host Capacity Model· May 14, 2026· 14 min· Mechanistic inference
Beyond Weight Loss: How GLP-1 Agonists Influence Gut Bioenergetics and the Host Capacity Model
Emerging research suggests GLP-1 receptor agonists do more than regulate glucose and appetite. They also influence colonocyte mitochondrial function, the gut oxygen gradient, the microbiome, and barrier integrity, with direct relevance to the Host Capacity Model.
#glp-1#semaglutide#colonocyte-bioenergetics
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