Question 1

What causes recurrent SIBO?

Accepted Answer

The Host Capacity Model identifies colonocyte bioenergetic failure as the upstream driver of recurrent SIBO. When colonocyte mitochondrial respiration fails, oxygen leaks into the lumen and reshapes the ecology toward facultative and sulfidogenic overgrowth—so antimicrobials clear the symptom but not the cause.

Question 2

How is MCAS different from other mast cell conditions?

Accepted Answer

BiomeLogic stratifies MCAS into Pattern A/B/C/D activation phenotypes based on upstream drivers (barrier, neuroimmune, infectious, or connective-tissue mediated). Treatment differs by pattern, which is why generic mast-cell stabilizers fail in many patients.

Question 3

Do you provide medical care or diagnoses?

Accepted Answer

No. BiomeLogic provides independent systems-biology consultation and mechanistic case analysis. It is not medical care, not a diagnosis, and does not replace your physician.

Long-form mechanistic writing.

The Single Molecule Driving Both Your SIBO and Your MCAS (And Why Nothing Has Worked)

The Real Cause of SIBO — Why Everything You’ve Been Told Is Incomplete

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