The limits are published alongside the reasoning.
- Evidence tiers
Every article carries an explicit evidence tier, so established biology is never presented as if it were clinical proof.
Read the claim ledger - What this does not prove
Mechanistic pieces are required to state their own limits and the competing explanations that would fit the same data.
See the counterarguments - Published corrections
Where the reasoning has been revised, the revision is recorded rather than quietly edited away.
Review the standards
Pick the sentence that sounds like your situation.
- Why does my SIBO keep coming back?
- Are SIBO breath tests actually reliable?
- Why don't antihistamines settle my symptoms?
- Can I have mast cell activation with normal tryptase?
- Why won't my Long COVID symptoms resolve?
- Why did COVID trigger this in me and not others?
- Why are my labs normal when I feel terrible?
- Why doesn't my stool test match my symptoms?
- Why does every protocol stop working after two weeks?
- Why did butyrate or probiotics make me worse?
- What do bile acids have to do with my gut symptoms?
- Can gut health affect my hormones and egg quality?
Educational mechanistic writing. It does not diagnose, and it does not replace the clinician treating you.
Seven mechanistic threads run through this library.
Recurrent SIBO & breath-test interpretation
16 articles · recurrent SIBO
Mast-cell activation, tryptase & histamine
23 articles · mast cell activation
Long COVID, post-viral gut–immune & POTS
18 articles · Long COVID gut symptoms
Colonocyte bioenergetics, butyrate & oxygen
20 articles · colonocyte bioenergetics
Bile acids, TUDCA & C. difficile ecology
7 articles · bile acid dysfunction
Gut–hormone axis, fertility & estrobolome
8 articles · gut microbiome and fertility
Lab-pattern interpretation
6 articles · lab pattern interpretation
8 articles
- SIBO· October 25, 2026· 25 min· Mechanistic inference
What If We’re Missing Something About ADHD and Autism? The Biology That Begins Before Birth
Maternal Immune Activation, GABA Signaling, Epigenetics, the Gut Microbiome, and the Early Development of a Brain Built for Survival
#bile-acids#estrogen#progesterone - MCAS & Mast Cells· October 20, 2026· 28 min· Mechanistic inference
Immunoadsorption (IA): The German Therapy That Removes Autoantibodies From the Blood — Could It Change the Future of Autoimmune Disease?
Over the past several months, I have been spending considerable time investigating a treatment called immunoadsorption, commonly abbreviated as IA.
#mcas#long-covid#dysautonomia - SIBO· October 7, 2026· 20 min· Mechanistic inference
When the Gut Changes, the Brain Does Not Read the Diagnosis: What One Pediatric Autism/ADHD Case Taught Me About Phenols, Mucosal Immunity, FMT, Streptococcus, and Metabolic State
I have been working through a pediatric case that has made me think deeply about the way we approach children with autism, ADHD, childhood apraxia of speech, PANS-like symptoms, gastrointestinal dysfunction, histamine intolerance, unusual
#gut#autism#adhd - SIBO· September 30, 2026· 29 min· Mechanistic inference
10 Things I Have Learned About Long COVID From Client Data and Research
I have not written in depth about Long COVID for a while, although it has continued to appear repeatedly in the complex cases I analyze.
#long-covid#sibo#pots - Host Capacity Model· September 27, 2026· 29 min· Mechanistic inference
FKBP5, Cortisol, Childhood Environment, Epigenetic Programming, and the Developmental Biology Behind ADHD and Other Neuropsychiatric Phenotypes
One of the areas I have been working on is trying to understand what happens when genetics, childhood environment, stress physiology, and neurodevelopment are no longer treated as separate subjects.
#ocd#adhd#bile-acids - SIBO· September 23, 2026· 25 min· Mechanistic inference
10 Things I Learned About SIBO That Explain Why It Keeps Coming Back
The more I study SIBO and work through people who have been dealing with it for years, the less I think the most important question is simply what will kill the bacteria.
#sibo#bile-acids#hormones - Host Capacity Model· September 11, 2026· 24 min· Mechanistic inference
ADHD Is Not Simply “Low Dopamine”: What Studying the Biology and My Own Genetics Has Taught Me
I have been looking into ADHD biology for a very long time, particularly the genetic and molecular side of it, and because I have ADHD myself and have been formally diagnosed with it, this subject has always been personal to me as much as
#adhd#serotonin#dopamine - SIBO· September 7, 2026· 35 min· Mechanistic inference
The Histamine Problem Nobody Explains: Why Some People Suddenly Start Reacting to Everything
The more I research histamine, and the more I work through complex cases involving MCAS, POTS, dysautonomia, SIBO, food reactions, gastrointestinal dysfunction, hormonal changes, medication sensitivities, flushing, itching, headaches
#sibo#mcas#histamine
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