- Mitochondria·May 25, 2026· 5 min·Mechanistic inferenceEducational only
Ulcerative Colitis Starts in the Mitochondrion
For forty years the field treated UC as immune dysregulation. The 2024 and 2025 literature finally admits what was upstream all along.
#ulcerative-colitis#ibd#mitochondria#colonocyte#butyrate-oxidation#oxygen-gradient#bioenergetics#host-capacity-modelRead mechanism → - Mitochondria·May 11, 2026· 7 min·Mechanistic inferenceEducational only
Incomplete Autophagy and the Long COVID Lock-In: A Mechanistic Lens
I keep stumbling into the same intersection from different directions. For the last few weeks I’ve been pulling on a thread that started innocently — a question about why some post-COVID patients respond dramatically to extended fasting while others crash. The literature on SA…
#long-covid#autophagy#mitophagy#mitochondria#post-viral#bioenergetics#host-capacity-modelRead mechanism →
Subscribe
Receive new articles.
New mechanistic essays delivered when published. Compatible with the existing Substack readership at @mohammedattallah.