HCM Mechanism Simulator

A live ODE model of the Host Capacity cascade. Adjust the three drivers. The six state variables respond in real time. Baseline healthy = 1.0.

Butyrate
intracellular concentration
1.00
NAD+
mitochondrial pool
1.00
SIRT3
activity
1.00
ATP
colonocyte output
1.00
O₂ consumption
epithelial rate
1.00
Hypoxia
luminal depth
1.00

Educational model. RK4 integration of a 6-variable coupled ODE system. Parameters normalized to healthy baseline = 1.0. Not a clinical tool.