What causes recurrent SIBO?

The Host Capacity Model identifies colonocyte bioenergetic failure as the upstream driver of recurrent SIBO. When colonocyte mitochondrial respiration fails, oxygen leaks into the lumen and reshapes the ecology toward facultative and sulfidogenic overgrowth—so antimicrobials clear the symptom but not the cause.

How is MCAS different from other mast cell conditions?

BiomeLogic stratifies MCAS into Pattern A/B/C/D activation phenotypes based on upstream drivers (barrier, neuroimmune, infectious, or connective-tissue mediated). Treatment differs by pattern, which is why generic mast-cell stabilizers fail in many patients.

Do you provide medical care or diagnoses?

No. BiomeLogic provides independent systems-biology consultation and mechanistic case analysis. It is not medical care, not a diagnosis, and does not replace your physician.

Free assessment

Host Capacity Score

18 questions. 6 mechanistic axes. A personalized read on where your physiology is straining — and what likely drives it.

Educational. Not a diagnosis. ~3 minutes.

0/18 answered0%

Q01I wake up rested and energetic.

Q02I crash heavily after mild exertion or stress.

Q03My energy is stable through the afternoon.

Q04I react to multiple foods that previously felt fine.

Q05I have bloating, gas, or distension after meals.

Q06My stools are well-formed and regular.

Q07I have taken multiple antibiotic courses in the last 5 years.

Q08I have used PPIs (omeprazole, etc.) for over 3 months.

Q09I tolerate fermentable foods (onion, garlic, beans, fruit) well.

Q10I flush, itch, or get hives without clear cause.

Q11Strong scents, alcohol, or histamine-rich foods trigger symptoms.

Q12Antihistamines noticeably reduce my symptoms.

Q13I can exercise moderately without next-day payback.

Q14I feel mentally sharp throughout the day.

Q15I recover quickly from infections or physical stress.

Q16I feel hung over for more than a day after one drink.

Q17Short sleep wrecks me for several days.

Q18I bounce back from late nights and stress quickly.

Anything else weighing on you?

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Pattern Atlas (optional). I agree that de-identified, non-personal pattern-level information from my submission may be used to improve BiomeLogic's educational pattern atlas and public mechanistic observatory. My personal information, uploaded files, and identifiable health details will not be publicly shared.

Educational systems-biology consulting · Not diagnosis
Not diagnosis or treatment
Works alongside your licensed care team
Written mechanistic summary
Fictional sample report available
No files required for Gate 1

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