Counterargument
What if the Host Capacity Model overgeneralizes?
A single framework that attempts to explain SIBO, MCAS, and post-viral illness risks overreach.
Where it is valid
Any framework attempting cross-syndromic synthesis must guard against framework inflation.
What it challenges
The breadth of HCM claims and their generalisation across complex syndromes.
Host Capacity Model response
HCM is scoped through Gate 1 fit screening, explicit model-boundary statements, and a public claim ledger that classifies every major claim by evidence tier. The framework is offered as one mechanistic lens among several, not a universal model.
Unresolved questions
- What proportion of cases in each syndrome cluster are well-described by HCM?
- Where does HCM produce false positives in case selection?
Evidence that would resolve this
- Independent replication of host-capacity framing in cohorts the framework did not select.