How Dysbiosis Disrupts Hormonal Health, Ovulation, and Egg Quality From the Inside Out — section

The fertility conversation has become overwhelmingly hormone-centric, but one of the most important mechanistic layers is still being underappreciated: the inflammatory dialogue between the gut microbiome and the ovary itself. Most people have heard of the &#8220;estrobolome,&#8221; the concept that gut bacteria regulate estrogen recycling through &#946;-glucuronidase activity and enterohepatic circulation. That mechanism is real, but it is incomplete. Dysbiosis does not merely alter how much estrogen circulates systemically. It can directly impair the ovarian machinery responsible for producing estrogen at the follicular level. This is the aromatase paradox.