Why Some People Never Recover From Gut Disorders: The Overlooked Genetic Architecture Driving Butyrate Failure, Dysbiosis, and Chronic Symptoms — Closing Reflection

Chronic gut disorders do not arise because &#8220;bad bacteria took over.&#8221; They arise because the host terrain lost its metabolic stability &#8212; and genetics determines how fragile that stability is. The future of gut medicine will not be generic protocols. It will be host-genomic stratification , personalized metabolic rehabilitation, and targeted restoration of epithelial energy pathways. This work is only the beginning, but the direction is clear: the terrain dictates the disease, the severity, and the recovery &#8212; not the microbe alone.