When the Gut Lowers the Seizure Threshold — section

Gut stress &#8211; whether from infection, inflammation, constipation, dysbiosis, or bile acid toxicity &#8211; impairs mitochondrial function in the intestinal epithelium. That mitochondrial failure disrupts butyrate oxidation. When butyrate can&#8217;t be oxidized, oxygen consumption falls. Oxygen leaks into the lumen. Barrier integrity weakens. Microbial metabolites and immune triggers escape containment.