What Actually Causes IBD? A Mechanistic Reading of Crohn's Disease and Ulcerative Colitis — Frequently asked questions about Crohn's disease and ulcerative colitis

Is IBD curable? Cure is the wrong framing. Most IBD patients will continue to manage the condition over their lifetime. The clinically useful framing is durable remission, where the disease is quiescent, medications are at their lowest effective dose, and the patient is functioning normally. Bioenergetic restoration extends the durability of remission and reduces the rate of relapse. It does not eliminate the underlying susceptibility, which has substantial genetic contributions in many cases. Can I come off my biologic? That is a decision made with your gastroenterologist, not with Biomelogic. The Host Capacity Model framework is not a strategy for stopping medication. It is a strategy for addressing the upstream lesion so that the medications do less work over time. Some patients, with their gastroenterologist's supervision, reduce medication dosing as the upstream work proceeds. Others remain on their current regimen indefinitely. The medication decision is medical care and belongs with the medical clinician. Is the Host Capacity Model recognized by IBD specialists? Not yet in this specific form. The colonocyte bioenergetic angle is increasingly recognized in the primary research literature, particularly in the work of Bäumler, Litvak, Donohoe, and others. The Roediger 1990 paper is finally being cited more frequently. The integration of these findings into a clinical framew