How Dysbiosis Disrupts Hormonal Health, Ovulation, and Egg Quality From the Inside Out — section

The consequence is not simply &#8220;low estrogen.&#8221; The consequence is compartmentalized ovarian endocrine collapse. Local estrogen synthesis inside the follicle becomes impaired even when systemic hormone panels appear relatively normal. Follicles arrest during development, meiotic maturation becomes defective, chromosomal segregation errors increase, mitochondrial ATP production declines, and ovulatory capacity deteriorates. This may help explain why some women present with infertility, poor egg quality, recurrent implantation failure, or irregular ovulation despite &#8220;normal&#8221; circulating estradiol measurements.