Beyond Weight Loss: How GLP-1 Agonists Influence Gut Bioenergetics and the Host Capacity Model — References

Greiner, T. U., Koh, A., Peris, E., Bergentall, M., Johansson, M. E. V., Hansson, G. C., Drucker, D. J., &amp; B&auml;ckhed, F. (2024). GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota. Molecular Metabolism , 83, 101924. Chakrabarti, S. K. (2025). Extending Healthspan via GLP-1 Receptor Agonists. Exploratory Research and Hypothesis in Medicine . Old, V. J. (2025). The Effects of Glucagon-Like Peptide-1 Receptor Agonists on Skeletal Muscle Mitochondrial Function in Obesity and Type 2 Diabetes: A Systematic Review. Nutrients , 17(10). This article is mechanistic analysis intended to support your understanding of GLP-1 signaling in the context of gut bioenergetics and your engagement with your medical team. It is not medical diagnosis or treatment advice. Mohammed Attallah is not a licensed clinician. Work with a qualified practitioner familiar with metabolic medicine, mucosal immunology, mitochondrial bioenergetics, and the integrated physiology of complex chronic illness to develop interventions appropriate to your specific case.