The Iron-Sulfur Cluster Crisis: Why Your Mitochondria Can't Recover (And Why Practitioners Don't Talk About It) — What Now?

If you&#8217;re interested in investigating whether Fe-S cluster dysfunction is part of your story&#8212;whether iron and sulfur homeostasis are driving your relapsing dysbiosis and mitochondrial symptoms&#8212;that requires a different kind of analysis. It requires looking at iron metabolism markers (ferritin, serum iron, TIBC), sulfur-dependent pathways (organic acids for sulfation capacity), microbial metabolites (H2S producing potential from shotgun metagenomics), and markers of mitochondrial health (NAD+ availability, Complex activity, ATP production). It also requires understanding how dysbiosis specifically disrupts your iron and sulfur ecology&#8212;not just generalized microbiome concepts. This is where consultation comes in. Understanding whether Fe-S cluster disruption is a primary driver of your condition&#8212;and if so, what that means for your path forward&#8212;requires analysis you won&#8217;t find in standard practice. If you want to explore whether this missing piece is part of your picture, I&#8217;m available for case consultation. We&#8217;d look at your specific biochemical markers, your dysbiosis pattern, and your colonocyte&#8217;s capacity to maintain Fe-S cluster homeostasis. Because until that infrastructure is addressed, relapse is predictable. And that&#8217;s a pattern worth breaking. Mohammed Attallah is an independent systems biology researcher