The Epigenetic Truth About Why Your Mast Cells Won’t Calm Down (And How to Actually Fix It) — section

That release &#8212; called degranulation &#8212; is what causes the symptoms associated with mast cell activation: flushing, hives, swelling, GI cramping, brain fog, heart palpitations, breathing difficulty. In the right context, degranulation is protective. It&#8217;s your immune system doing exactly what it should.