The Mycotoxin-Mitochondria Trap: Why Standard Detox Fails in Chronic Illness, and How to Escape It — Escaping the Mycotoxin-Mitochondria Trap: A Host Capacity Approach

A more comprehensive approach, aligned with the Host Capacity Model, addresses the upstream lesion rather than only the toxin itself. The components are conceptual and intended for clinician discussion, not personal protocol. Restoring mitochondrial function. Strategies that support mitochondrial biogenesis, electron transport chain efficiency, and antioxidant capacity, integrated with the rest of the case. Re-establishing the gut oxygen gradient. Supporting colonocyte bioenergetics so the natural hypoxic environment of the colonic lumen can re-form, allowing the obligate anaerobic community and barrier integrity to recover. Addressing inflammation. Identifying and modulating chronic inflammatory pathways that perpetuate energy drain and hinder detoxification capacity. Strategic binding and elimination. Using binders judiciously, in coordination with the foundational host-capacity work, so the body can effectively process and excrete what is being mobilized.