Why hEDS, POTS, and MCAS Almost Always Come Together: The Mechanistic Triad and the Upstream Lesion Standard Medicine Doesn't Treat — How I Work With This

Biomelogic is an independent systems biology consulting practice that reads complex cases at the bioenergetic and integrative layer that the standard treatment model does not address. The triad is one of the most common reasons patients reach out, alongside chronic SIBO, long COVID, and the broader category of host capacity limited illness. The work I do is mechanistic case analysis. I integrate your full longitudinal history, your laboratory data, your symptom pattern across the three subsystems, your prior intervention history, and the integrated convergence framework I have described in this essay into a defensible model of where the upstream lesion lives in your specific case, what the intervention sequence should look like, and what to communicate to your medical team about each component. I do not prescribe, diagnose, or replace your medical team. I do the integrative analytic work that the standard appointment does not have time for, and I deliver it in a form your existing clinicians can review, discuss, and act on. The patients I work with are typically two to five years into the triad, have run extensive specialist workups, have tried multiple single diagnosis interventions, and have reached the point where more of the same is not going to resolve the illness. The standard consultation is $650 and includes full case review, a ninety minute live session, and a written